![]() ![]() Walt, one of the study’s authors, told The Guardian that the presence of the spike protein indicated such a reservoir as the half-life of this antigen is “pretty short” in the body.ĭr. The researchers believe that the presence of SARS-CoV-2 spike protein in a majority of long COVID patients up to 12 months post-diagnosis suggests the presence of an active persistent SARS-CoV-2 viral reservoir.ĭr. Moore, professor of microbiology and immunology at Weill Cornell Medicine, who was not involved in the study, told Medical News Today. “The most logical interpretation is that spike protein in serum is a surrogate marker for a persistent infection somewhere in the body,” Dr. The long COVID ‘viral reservoir’ hypothesis The S1 subunit and nucleocapsid were detected in the blood of COVID-19 patients immediately after the COVID-19 diagnosis, but the levels of these antigens quickly dropped below the limit of detection. In contrast, the researchers did not detect spike protein in any of the patients with typical COVID-19 infection. Out of the three SARS-CoV-2 antigens, the spike protein was the most common, having been detected in 60%-or 3 out of 5-of long COVID patients. The researchers found that the spike protein, S1 subunit, or nucleocapsid were present in the blood of 65% of the long COVID patients they tested, up to 12 months after their initial COVID-19 infection. Nucleocapsid – nucleic acid (genetic material) and surrounding capsid (protein coat) of the virus.S1 subunit of spike protein – one of two subunits that make up the spike protein.Spike protein – spike-like molecules that protrude from the surface of the SARS-CoV-2 virus.They sought to determine the levels of three SARS-CoV-2 antigens: ![]() "We got some advice once that if you can’t do it as hometown boys in Erie, you’re not going to do it in any other market," Kurczewski said.To identify a blood biomarker for long COVID, researchers at Harvard Medical School and the Ragon Institute of MGH, MIT and Harvard, analyzed blood plasma samples collected from patients with long COVID and typical COVID-19 infection over a period of 12 months. It would've just gotten lost in the weeds." "I don’t think our product would’ve gained as much attention or notoriety if (the launch) was in a big city. "I think it helps that in Erie, it’s a pretty cool tight-knit community," Clark said. Launching their product in Erie-or the Miami of the North, as they call it- was a no-brainer. They have an interest in reaching students at Pennsylvania State University, University of Pittsburgh and possibly Ohio State University in Columbus, Ohio. Protochol is an alcoholic protein drink.Ĭlark, Kurczewski and Prischak hope to expand Protochol's reach beyond the Erie area to the State college market by the start of the fall semester, Clark said. Protochol Co-Founders Mitch Clark, left, and Joshua Kurczewski are interviewed on Feb. So, in their parents' basements, they began mixing whey protein powder with various alcohols, coming up with a few "unfortunate" combinations, Clark said. New business: Purrista Cat Cafe to open in downtown Erie, offering coffee plus felines available for adoptionĪs avid gym-goers, Kurczewski, Clark and Prischak wanted to create a drink that appealed to their gym and social lifestyles. "We went down some weird rabbit holes, like trying to solve the shortage of blood being donated, but then we thought, 'You know what would be a lot easier? Making something we would normally drink rather than try and make a supply chain software program.'" "We really just wanted to start a business," Kurczewski, 23, said. "We’ve already had a couple stores have to reorder after selling out pretty quickly, so we’re pretty happy with how things are going." Humble beginningsĪfter graduating from their respective colleges in May 2020, the co-creators - who attended Cathedral Preparatory School together - found themselves back in their hometown wondering what to do with some free time. "The taste reviews have definitely been great," Clark, 24, said. ![]()
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